Important Notice: Please read these Terms of Use
carefully before accessing or using any content or services provided on this
website (the “Site”). By accessing, browsing, downloading, installing, or
otherwise using the Site, you acknowledge that you have read, understood, and
agreed to be bound by these Terms of Use, which constitute a legally binding
agreement between you and Cobioer Biosciences , together with its affiliates
(“we” or “us”).
These
Terms of Use take effect on the earlier of:
(a)
the date you first access or use any part of the Site or its services; or
(b)
the date on which you indicate acceptance of these Terms.
If
you do not agree to any part of these Terms of Use, you must immediately discontinue
use of the Site and its services.
Cell-Panorama
is a comprehensive Tumor Cell Models and Engineered Cell Modles database
developed by Cobioer Biosciences, offering research- and drug
development–related data, information resources, and supporting services,
including but not limited to database search, analysis, visualization tools,
and technical research support. These Terms define users’ rights, obligations,
and responsibilities in connection with use of the Site.
We
reserves the right to revise these Terms from time to time. Any updated version
becomes effective upon publication on the Site. Continued use of the Site
following such updates constitutes acceptance of the revised Terms.
If
you have registered for an account and no longer agree with these Terms, you
may request deletion of your registration information in accordance with the
Privacy Policy.
II. Research Responsibility and Compliance
All
scientific data, research-related information, analytical outputs, and
reference materials made available through this Site are provided on an
“as is” and “as available”
basis. We make no
representations or warranties of any kind, whether express or implied,
regarding the accuracy, completeness, timeliness, reliability, fitness for a
particular research purpose, or non-infringement of any such information or
data. The information provided may not be current and may be subject to
revision or update without notice.
Any
interpretations, analyses, research conclusions, experimental designs, or
research and development outcomes derived from the use of this Site or its
databases are generated at your own discretion and risk. We do not warrant or
guarantee any specific research results, experimental outcomes,
reproducibility, technical feasibility, regulatory acceptability, or scientific
validity arising from the use of the information provided. You acknowledge that
use of the Site does not replace independent scientific evaluation,
experimental verification, or professional judgment.
You
are solely responsible for ensuring that any research activities, experiments,
development work, or downstream applications conducted based on or informed by
the use of this Site comply with all applicable laws, regulations, ethical
standards, and industry guidelines, including but not limited to those relating
to biomedical research, laboratory practices, data usage, biosafety, and
regulatory compliance. We assume no responsibility for your compliance
obligations or regulatory responsibilities.
To
the fullest extent permitted by applicable law, Cobioer Biosciences makes no
representations, warranties, or assurances regarding regulatory approvals,
clinical success, commercialization, market acceptance, or any other business
or financial outcomes that may result from the use of the Site, databases, or
related information.
Access
to this Site may be unavailable, interrupted, or insecure at times due to
technical issues, maintenance, cyber incidents, or other factors beyond our
reasonable control. We do not warrant that any content or materials accessed or
downloaded through the Site or linked websites will be free from viruses or
other harmful components. To the fullest extent permitted by applicable law, we
shall not be liable for any loss or damage arising from your use of the Site,
including those resulting from cyberattacks, malware, system failures, or loss
of data or equipment.
III. Eligibility and Legal Capacity
You
represent and warrant that you have full civil capacity under the laws of the
People’s Republic of China and are legally capable of entering into and
performing these Terms.
If
you are a minor, you may only use the Site with the consent and guidance of
your legal guardian, who should carefully review the provisions applicable to
minors in the Privacy Policy.
If
you access the Site on behalf of your employer or another entity, you represent
that you are duly authorized to bind such entity, and these Terms shall be
binding on both you and that entity.
IV. Cell-Panorama
Database and Services
4.1 Overview
The Cell-Panorama database is a proprietary
platform independently developed and continuously maintained by Cobioer
Biosciences. It comprises Tumor Cell Models database and
Engineered
Cell Models
database, designed to support pharmaceutical companies,
biotechnology enterprises, and research institutions with structured research-reference
data.
4.2 Tumor Cell Models
Database
The Tumor Cell Models Database is an
integrated bioinformatics platform that consolidates large-scale tumor cell
line datasets, including but not limited to:
1)
Whole Exome Sequencing (WES) data
2)
RNA Sequencing (RNA-seq) data
3)
Signaling pathway and functional annotation
data
4)
Drug sensitivity data (e.g., IC50 values)
Covering tumor cell models across multiple
cancer types, the database systematically correlates cellular genetic variation
data with pharmacological sensitivity data to generate a comprehensive
landscape of tumor cell models, supporting target research, mechanism studies,
and early-stage drug screening.
4.3 Engineered Cell
Models Database
The Engineered Cell Models Database comprises
a diverse collection of genetically engineered cell models, including but not
limited to:
1)
Kinase-related engineered cell models
2)
Immunology and immuno-oncology cell models
3)
GPCR engineered cell models
4)
Drug resistance models
5)
Tracing and reporter system models
The database provides structured information
on screening- and assay-qualified cell models for over 500 drug-related
targets, supporting pharmaceutical companies in early-stage target discovery
and candidate screening, as well as in later-stage bioassay validation,
antibody characterization, and quality release testing.
4.4 Platform Features
1)
User-friendly interfaces suitable for users
at different levels
2)
Multi-criteria search, filtering, and data
display tools
3)
Data visualization and customizable user settings
4)
Reasonable technical and organizational
measures to protect system and data security
4.5 Research-Only
Positioning
You expressly acknowledge and agree that:
1)
All content provided by the Cell-Panorama
database is for research and drug discovery reference purposes only
2)
The platform does not provide medical advice,
clinical diagnosis, treatment recommendations, or prescribing guidance
3)
Database content may not be used directly for
clinical decision-making or patient care
V. Account Registration and Management
Certain
features of the Site may require users to register an account. When
registering, you agree to provide true, accurate, and complete information and
to keep such information up to date.
You
are responsible for maintaining the security and confidentiality of your
account credentials, including your username and password, and for all
activities conducted under your account, whether or not authorized by you.
You
shall promptly notify us of any unauthorized use of your account or any other
security breach. We shall not be responsible for any loss or damage arising
from your failure to properly safeguard your account information or to provide
timely notice.
You
may use the Site and its content only for lawful purposes and in accordance
with these Terms of Use. Without our prior written consent, you agree not to:
l
Violate
any applicable laws, regulations, or policies, including intellectual property
rights and data protection laws.
l
Impersonate
Cobioer, its employees, other users, or any other person or entity.
l
Use the
Site to transmit unsolicited advertising, promotional materials, or spam,
including bulk emails or chain messages.
l
Access,
copy, scrape, download, or distribute database content using automated tools,
scripts, crawlers, or other devices, except as explicitly permitted by the
Site.
l
Attempt
to gain unauthorized access to the Site, its servers, databases, or any
connected systems.
l
Introduce
viruses, malware, ransomware, spyware, or any harmful software or code.
l
Interfere
with the operation, security, or functionality of the Site, including
conducting denial-of-service or distributed denial-of-service attacks.
l
Use the
Site in a way that could disrupt other users
’ access, data analysis, or research activities.
l
Create derivative
databases, mirror or reproduce substantial parts of the Site, or use its data
for commercial redistribution without explicit written authorization.
l
Reverse
engineer, decompile, or attempt to derive the source code, architecture, or
underlying data structure of the Site or its software.
Violation
of any of the above may result in account suspension, termination, or legal
action.
VII. Intellectual Property and Confidentiality
7.1 Ownership and Protection
The
Site, including all databases, content, software, designs, graphics, text,
images, videos, audio, and other materials (collectively “Content”), is
protected by applicable copyright, trademark, patent, trade secret, and other
intellectual property laws. All rights, title, and interest in the Content
belong to Cobioer Biosciences or its licensors, affiliates, or other rightful
owners. You do not acquire any rights or licenses to the Content except as
expressly granted in these Terms of Use.
7.2 Trade Secrets and Confidential Information
The
databases and underlying data, including the Cell-Panorama Tumor Cell Models
and Engineered Cell Models data, constitute Cobioer’s proprietary trade
secrets. You shall treat all such data and information as strictly confidential
and take protective measures no less stringent than those you use to protect
your own confidential information, but in no event less than reasonable care.
You may not disclose, reproduce, distribute, transmit, or use such data for any
purpose not explicitly authorized by Cobioer in writing.
7.3 Restrictions on Use
Without
prior written consent from Cobioer, you may not:
l
Copy,
modify, republish, perform, display, download, or transmit any part of the Site
or Content;
l
Create
derivative works or competing databases;
l
Remove,
obscure, or alter any intellectual property notices or confidentiality legends
on the Content;
l
Use the
Site or its Content in a manner that infringes any intellectual property rights
or other rights of Cobioer or third parties.
7.4 Respect for Third-Party Rights
Cobioer
respects the intellectual property rights of others. If you believe that your
intellectual property rights have been infringed on this Site, please contact
Cobioer with all relevant details.
7.5 Survival of Obligations
Your
obligations regarding intellectual property rights and confidentiality survive
the termination or expiration of your account or access to the Site.
VIII. User Submission of Information
When
you upload, submit, or otherwise provide any content, materials, or information
through this Site (“User Submissions”), we will process only such information
as is reasonably necessary to operate the Site and provide the relevant
services.
All
User Submissions shall be deemed non-confidential unless otherwise expressly
agreed in writing. By submitting User Submissions, you grant us and our
authorized partners a limited, non-exclusive, royalty-free license to use,
reproduce, display, and process such submissions solely for the purposes for
which they are provided or as necessary to operate and improve the Site.
We
will not collect or use personal information beyond what is reasonably required
to achieve the above purposes.
Permitted Use of User Submissions
We
may use User Submissions for the following purposes:
l
Operating,
maintaining, optimizing, and promoting the Site and related services;
l
Making
reasonable technical adjustments to User Submissions, including formatting,
resizing, or editing, where necessary to ensure proper display or
functionality.
l
We will
not sell or disclose your personal information for marketing or commercial
purposes without your prior explicit consent.
What We Collect and Why
We
collect only the information necessary for legitimate business operations or as
required by applicable laws, which may include:
l
Basic
contact information (such as name and email address) for account management,
communication, and support;
l
Technical
information such as IP address and login records for security, system
administration, and compliance purposes.
l
We may
also analyze anonymized or aggregated technical data to improve the
performance, security, and user experience of the Site.
Prohibited Submissions
You
agree not to submit any content that:
l
Is
false, misleading, or infringes upon the lawful rights or interests of others;
l
Contains
personal data unnecessary for your use of the Site or services;
l
Violates
applicable laws or regulations, or contains viruses, malicious code, or other
harmful components.
Your Rights
Subject
to applicable laws, you may have the right to:
l
Request
access to the personal information we hold about you;
l
Request
correction, deletion, or restriction of processing of your personal
information;
l
Object
to certain data processing activities conducted based on our legitimate
interests.
Data Protection
We
implement reasonable technical and organizational safeguards to protect
personal information against unauthorized access, disclosure, alteration, or
loss. Where disclosure of personal information is required by law, we will
comply with such obligations and notify you where legally permitted.
For
users located in jurisdictions requiring specific legal bases for processing,
personal information will be processed based on legitimate interests,
contractual necessity, or user consent, as applicable.
IX. Third-Party Links
This
Site may contain links to third-party websites or resources for reference or
convenience only. We do not control and are not responsible for the content,
accuracy, or availability of such third-party sites. Your access to any
third-party site is at your own risk and subject to the terms of such sites.
X. Limitation of Liability
To
the fullest extent permitted by law, the Site and its content are provided on
an “as is” basis. We shall not be liable for any direct or indirect,
incidental, consequential, or punitive damages arising out of or in connection
with your access to or use of the Site.
Nothing
in these Terms shall exclude or limit liability that cannot be excluded or
limited under applicable law.
XI. Indemnification
You
agree to indemnify and hold harmless the Company and its affiliates from any
claims, losses, liabilities, or expenses arising from your violation of these
Terms or misuse of the Site.
XII. Governing Law and Dispute Resolution
These
Terms shall be governed by and construed in accordance with the laws of the
People’s Republic of China. Any dispute arising out of or relating to these
Terms or the Site shall be submitted to arbitration before the Nanjing Arbitration Commission,
with the arbitral award being final and binding.
重要提示:在访问或使用本网站(以下简称
“
本网站
”
)提供的任何内容或服务之前,请您仔细阅读本《网站使用条款》(以下简称
“
本条款
”
)。一旦您访问、浏览、下载、安装或以任何方式使用本网站,即视为您已充分理解并同意接受本条款的全部内容。本条款构成您与本公司及其关联方(以下统称
“
公司
”
或
“
我们
”
)之间具有法律约束力的协议。
本条款自以下时间中较早者起生效:
(1)您首次使用本网站或其任何服务之日;
(2)您以任何形式表示同意受本条款约束之日。
如您不同意本条款的任何内容,请立即停止使用本网站及其服务。
数据库Cell-Panorama是由科佰生物创建的肿瘤细胞模型全景数据库和靶向药物工程细胞模型数据库,向用户提供科研与药物研发相关的数据、信息资源及配套服务,包括但不限于数据库查询、分析、展示工具及研究支持服务。本条款规定了用户在使用本网站过程中的权利、义务及相关责任。
公司有权根据实际需要不时修订本条款。修订后的条款一经在本网站公布即生效。用户在条款更新后继续使用本网站的,视为已接受修订后的条款。
若您已注册账户且不再同意本条款,可依据隐私政策要求删除您的注册信息。
二、研究责任与合规声明
本网站所提供的所有科学数据、研究相关信息、分析结果及参考资料,均按照“现状提供(as is)”及“可获得状态(as available)”提供。本公司不就该等信息或数据的准确性、完整性、及时性、可靠性、特定科研用途适用性或不侵权性作出任何明示或默示的声明或保证。相关信息可能并非最新内容,且可能在不另行通知的情况下发生变更或更新。
任何基于本网站或其数据库所形成的解释、分析、研究结论、实验设计或研发结果,均由您自行判断并自行承担相应风险。本公司不保证亦不承诺因使用本网站信息而获得的任何特定研究结果、实验结论、重复性、技术可行性、监管可接受性或科学有效性。您确认并理解,使用本网站信息不应替代独立的科学评估、实验验证或专业判断。
您应自行确保,任何基于本网站信息开展的研究活动、实验、开发工作或后续应用,均符合所有适用的法律法规、伦理规范及行业准则,包括但不限于生物医学研究、实验室规范、数据使用、生物安全及监管合规方面的要求。本公司不对您的合规义务或监管责任承担任何责任。
在适用法律允许的最大范围内,科佰生物不就因使用本网站、数据库或相关信息可能产生的任何监管审批结果、临床成功、商业化进展、市场接受度或其他商业或财务结果作出任何声明、保证或承诺。
因技术问题、系统维护、网络攻击或其他超出本公司合理控制范围的因素,本网站的访问可能出现不可用、中断或安全风险。本公司不保证通过本网站或其链接网站获取或下载的任何内容或资料不含病毒或其他有害成分。在适用法律允许的最大范围内,因您使用本网站而产生的任何损失或损害,包括因网络攻击、恶意程序、系统故障或数据、设备丢失所导致的损失,本公司概不承担责任。
三、用户资格与法律能力
您确认,您已达到中华人民共和国法律规定的完全民事行为能力年龄,并具有签署和履行本条款的合法资格。
如您为未成年人,应在法定监护人的同意和指导下使用本网站,并由监护人认真阅读与未成年人相关的隐私条款。
如您代表您的雇主或其他组织使用本网站,您确认已获得充分授权,本条款对您及该组织均具有约束力。
四、
Cell-Panorama
数据库及服务内容
4.1
数据库概述
Cell-Panorama 数据库是由科佰生物自主创建并持续维护的肿瘤细胞模型全景数据库与靶向药物工程细胞模型数据库,面向药物研发企业、生物技术公司及科研机构,提供系统化、结构化的科研参考数据服务。
4.2
肿瘤细胞模型全景数据库
肿瘤细胞模型全景数据库是一个综合性的生物信息资源平台,集成并系统整理了海量肿瘤细胞系相关数据,包括但不限于:
1)
全外显子测序(WES)数据
2)
转录组测序(RNA-seq)数据
3)
信号通路与功能注释信息
4)
药物敏感性数据(如 IC50 等)
该数据库覆盖多种癌种的肿瘤细胞模型,通过将细胞的基因变异信息与药物药敏数据进行关联分析,构建肿瘤细胞模型的全景图谱,为药物靶点研究、机制探索及候选药物筛选提供科研支持。
4.3
靶向药物工程细胞模型数据库
靶向药物工程细胞模型数据库汇集了多种通过基因工程手段构建的工程化细胞模型信息,包括但不限于:
1)
激酶相关工程细胞模型;
2)
免疫与免疫肿瘤方向工程细胞模型
3)
GPCR 工程细胞模型;
4)
耐药机制相关模型;
5)
示踪与报告系统细胞模型;
该数据库涵盖500 多个与药物研发相关的靶点,为筛选细胞模型、检定细胞模型及生物活性检测提供系统化信息支持,广泛应用于:
药物早期研发阶段的靶点候选物发现与筛选和抗体、蛋白药物等在研发及放行阶段的生物学检定与质量控制。
4.4
平台功能
1)
提供用户友好的操作界面
2)
支持多维度搜索、筛选与数据展示
3)
提供数据可视化及个性化设置功能
4)
采取合理的安全措施保护系统与数据安全
4.5
数据库定位声明
您明确理解并同意:
1)
Cell-Panorama 数据库及其所有内容仅供科研与药物研发参考使用;
2)
本平台不构成医疗建议、临床诊断依据、治疗方案或用药指导;
3)
数据库内容不得直接用于任何临床决策或患者管理;
五、账户注册与管理
本网站的部分功能可能需要用户注册账户后方可使用。您在注册时应提供真实、准确、完整的信息,并在信息发生变更时及时更新。
您应妥善保管账户名、密码等账户信息,并对通过该账户进行的所有操作和行为承担责任,无论该等行为是否经您授权。
如发现账户被未经授权使用或存在其他安全风险,您应及时通知我们。因您未妥善保管账户信息或未及时通知而产生的任何损失或损害,我们不承担责任。
您仅可为合法目的使用本网站及其内容,并须遵守本《使用条款》。未经科佰生物书面许可,您不得:
l
违反适用法律法规及政策,包括知识产权和数据保护法律法规。
l
冒充科佰生物、其员工、其他用户或任何其他个人或实体。
l
利用本网站发送未经请求的广告、宣传资料或垃圾信息,包括群发邮件或链式信息。
l
使用自动化工具、脚本、爬虫或其他设备访问、复制、抓取、下载或分发数据库内容,除非本网站明确允许。
l
试图未经授权访问本网站、服务器、数据库或任何关联系统。
l
传播病毒、恶意软件、勒索软件、间谍软件或任何有害代码。
l
干扰本网站的运行、安全或功能,包括实施拒绝服务或分布式拒绝服务攻击。
l
以任何可能妨碍其他用户访问、数据分析或科研活动的方式使用本网站。
l
未经书面授权创建衍生数据库、镜像或复制网站大量内容,或将网站数据用于商业再分发。
l
反向工程、反编译或试图获取网站或其软件的源代码、架构或底层数据结构。
违反上述任意条款,可能导致账户被暂停、终止或面临法律责任。
七、知识产权与保密义务
八、用户提交信息
当您通过本网站上传、提交或以其他方式提供任何内容、材料或信息(统称“用户提交信息”)时,本公司仅会在合理必要的范围内处理相关信息,以用于网站运营及向您提供相应服务。
除非另有书面约定,所有用户提交信息均视为非机密信息。您提交用户信息即视为授予本公司及经授权的合作方一项有限的、非排他性的、免版税的许可,仅用于实现提交目的或网站正常运营、维护和改进所必需的用途。
本公司不会收集或使用超出上述目的所合理必需范围的个人信息。
用户提交信息的使用范围
本公司可能在以下范围内使用用户提交信息:
l
网站及相关服务的运营、维护、优化与推广;
l
为确保网站功能或展示效果,在合理必要范围内对用户提交内容进行技术性调整(如格式处理、尺寸调整或编辑)。
l
未经您事先明确同意,本公司不会出于营销或商业目的出售或披露您的个人信息。
信息收集范围及目的
本公司仅收集为合法业务运营或法律法规要求所必需的信息,包括但不限于:
l
用于账户管理、沟通和技术支持的基本联系方式(如姓名、电子邮箱);
l
出于安全、系统管理及合规需要所记录的 IP 地址及登录信息。
l
此外,本公司可能在不识别个人身份的前提下,对匿名化或汇总的技术数据进行分析,以提升网站性能、安全性和用户体验。
禁止提交的内容
您承诺不会向本网站提交以下内容:
l
虚假、误导性信息,或侵犯他人合法权益的内容;
l
与您使用本网站或相关服务无关的个人信息;
l
违反法律法规,或包含病毒、恶意程序及其他有害成分的内容。
用户权利
在适用法律允许的范围内,您依法享有以下权利:
l
查询和访问本公司持有的您的个人信息;
l
请求更正、删除或限制处理您的个人信息;
l
对基于本公司合法利益进行的特定数据处理活动提出异议。
数据保护措施
本公司采取合理的技术和管理措施,防止个人信息遭到未经授权的访问、披露、篡改或丢失。如法律要求披露个人信息,本公司将依法履行相关义务,并在法律允许的情况下通知您。
对于法律要求特定处理依据的司法辖区用户,本公司将根据合法利益、合同需要或取得用户同意等适用依据处理个人信息。
九、第三方链接
本网站可能包含指向第三方网站或资源的链接,仅供参考或使用便利之目的。本公司无法控制亦不对该等第三方内容的准确性、完整性或可用性承担责任。您访问任何第三方网站的风险由您自行承担,并应遵守其适用条款。
十、责任限制
在法律允许的最大范围内,本网站及其内容按“现状”提供。本公司不对因您访问或使用本网站而产生的任何直接或间接、附带性、继发性或惩罚性损失承担责任。
本条款不排除或限制依法不得排除或限制的任何责任。
十一、赔偿与保障
因您违反本使用条款或不当使用本网站而产生的任何索赔、损失或责任,您同意依法对本公司及其关联方予以赔偿并使其免受损害。
十二、适用法律与争议解决
本使用条款的订立、解释和履行均适用中华人民共和国法律。因本条款或本网站引起的或与之相关的任何争议,应提交南京仲裁委员会仲裁,仲裁裁决为终局,对双方均具有约束力。